GABAergic Activity

GABA is the primary inhibitory neurotransmitter. It calms neural activity.

Evidence note: L-theanine, ashwagandha, and bromantane influence GABA signaling.

EVIDENCE

supported

INGREDIENTS

What
affects it.

Inhibitory neurotransmitter. Precursor to collagen. Supports sleep quality.

Supports cardiac function, bile acid conjugation, and neurotransmission.

Produces calm focus. Often paired with caffeine.

Reduces cortisol in multiple RCTs. May improve testosterone and stress resilience.

Cofactor for neurotransmitter synthesis. P5P is the active form.

Cofactor in 300+ enzymes. Forms differ in bioavailability and GI tolerance [citation:27][citation:33].