Cortisol Modulation

Chronic cortisol elevation impairs recovery, sleep, and testosterone. Adaptogens may modulate it.

Evidence note: Ashwagandha reduces serum cortisol in multiple human RCTs.

EVIDENCE

supported

INGREDIENTS

BIOMARKERS

What it
changes.

Activating this pathway affects the following measurable biomarkers.

Adaptogen for stress and fatigue. May improve mood and endurance.

Human RCTs show testosterone increase in hypogonadal men [citation:37]. Aromatase inhibition shown in vitro.

Reduces cortisol in multiple RCTs. May improve testosterone and stress resilience.

Adaptogenic mushroom. Studied for immune function and stress.

Adaptogen studied for liver protection and stress resilience.