HOME/MECHANISMS/PDE
neurotransmitter · established

Phosphodiesterase Inhibition

PDE breaks down cAMP. Inhibiting PDE = signals last longer.

Evidence note: Caffeine inhibits phosphodiesterase, which slows cAMP breakdown.
EVIDENCE
established
INGREDIENTS
2

What
affects it.

stimulant
Caffeine

The most widely consumed psychoactive substance. Blocks adenosine, improves performance.

established$
stimulant
Theobromine

Milder stimulant than caffeine. Found in cocoa.

supported$

Contributes to these goals.

ALL GOALS →
🎯
Focus & Attention

Sustained attention, working memory, and task engagement.

🔥
Fat Loss

Reducing body fat while preserving muscle. Achieved through a combination of energy deficit, fat oxidation, and metabolic support.