HOME/MECHANISMS/ADENOSINE
neurotransmitter · established

Adenosine Antagonism

Adenosine makes you tired. Caffeine blocks it.

Evidence note: Caffeine blocks adenosine receptors, increasing energy and alertness.
EVIDENCE
established
INGREDIENTS
2
BIOMARKERS
1

What it
changes.

Activating this pathway affects the following measurable biomarkers.

↓
Reaction Time
ms
200–300 ms

What
affects it.

stimulant
Caffeine

The most widely consumed psychoactive substance. Blocks adenosine, improves performance.

established$
stimulant
Theobromine

Milder stimulant than caffeine. Found in cocoa.

supported$

Contributes to these goals.

ALL GOALS →
🎯
Focus & Attention

Sustained attention, working memory, and task engagement.

🏃
Endurance

Sustained aerobic capacity — VO2max, time to exhaustion, and lactate threshold.